Skip to main content

Dr Prashant Kadam

LIVER TRANSPLANT +
CANCER SURGERY +
LIVER TRANSPLANT
GALL BLADDER SURGERY +
BILIARY SURGERY +
CANCER SURGERY
LIVER TRANSPLANT +
PANCREATIC SURGERY
CANCER SURGERY +
LIVER TRANSPLANT
LIVER SURGERY +
CANCER SURGERY

Dr. Prashant Kadam

MBBS , MS , MRCS , M.Ch , FRCS , FEBS

Book Appointment

Advancements in Liver Preservation: How Machine Perfusion is Changing Transplant Outcomes

In the world of liver transplantation, one of the biggest challenges is organ preservation. Traditional cold storage has limitations—especially for marginal or older donor livers. That’s where machine perfusion technology is making a significant impact.

What is Machine Perfusion?

Machine perfusion involves pumping oxygenated blood or preservation fluid through the donor liver outside the body. This mimics natural circulation and keeps the liver “alive” until transplant.
There are two types:
  • Hypothermic Machine Perfusion (HMP): Uses cold, oxygenated fluid
  • Normothermic Machine Perfusion (NMP): Keeps the liver at body temperature with oxygen and nutrients

Why It Matters

Traditionally, donor livers could only be preserved for 8–12 hours with cold storage. Machine perfusion extends this window and allows surgeons to:
  • Better assess liver function before transplant
  • Improve organ recovery post-surgery
  • Use marginal or high-risk donor livers safely
  • Reduce the risk of organ rejection

Dr. Kadam’s Experience in the UK

During his training and clinical work in the UK, Dr. Prashant Kadam worked closely with machine perfusion protocols at Queen Elizabeth Hospital, Birmingham—a pioneer in transplant technology. He participated in clinical trials and real-world implementation of this technique, making him one of the few surgeons in India with hands-on expertise.

How It Helps Patients

  • Increases the number of usable donor organs
  • Improves graft function post-transplant
  • Reduces complications in the early post-op period
  • Saves lives by reducing waitlist mortality

Final Word

Machine perfusion is changing the future of organ transplantation. As the technology becomes more widely available in India, patients will benefit from safer surgeries, faster recovery, and better outcomes.
If you’re awaiting a liver transplant or want to understand your options, speak to a transplant surgeon with expertise in next-generation care.

Medically Reviewed by Dr. Prashant Kadam, MBBS, MS, MRCS, M.Ch., FRCS, FEBS — Consultant HPB & Liver Transplant Surgeon, Mumbai.

X-twitter
View Full Profile →

Schedule Appointment

Fill out the form below, and we will be in touch shortly.